MULTIDRUG RESISTANT BACTERIA - A THREAT TO PUBLIC HEALTH
Rozalina Yordanova and Hristina Milcheva
ABSTRACT: Over the past few decades, multidrug resistance has become an increasingly serious cause for concern and one of the most important current threats to public health worldwide. Multidrug-resistant (MDR) bacteria are commonly associated with nosocomial infections because they are easily retained and spread in the hospital environment, especially in intensive care clinics. However, some of them are common causes of community-acquired infections. Infections caused by MDR pathogens are increasingly difficult to treat with commonly used antibiotics, which is associated with increased morbidity, increased health care costs, limited treatment options, prolonged hospital stay and, in some cases, increased mortality. Objective: A review of current trends in multidrug-resistant bacteria and current treatment guidelines and a look at new antimicrobials and alternatives, as well as future considerations for combating antibiotic resistance on a global scale. Materials and methods: systematic review and analysis of scientific literature. Results and Conclusions: Multidrug-resistant bacteria are an important threat to public health, an outstanding challenge for therapeutic models. Further research, development and validation of rapid and reliable diagnostic techniques to identify resistance patterns are urgently needed to select best approaches and practices for the prevention and control of MDR infections. It is also necessary to study the role of new antimicrobial agents in the fight against multi-resistant pathogens, which would facilitate therapeutic options. Preventing the further spread of MDR bacteria, both in the community and in the hospital environment, remains one of the most important strategies to deal with these pathogens and requires a multidisciplinary approach and collaborative action at the global level.
Keywords: multidrug resistant bacteria, antimicrobial resistance, nosocomial infections